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The association between gastro-oesophageal reflux and migraine in the paediatric population: a multicentre case-control study.


ABSTRACT: Infantile regurgitation is one of the most common discomforts in the first months of life. Infantile colic and, in older children, functional dyspepsia have been linked to migraine. To date, this is the first study to investigate a possible association between infantile regurgitation and primary headaches in children. This is a case-control study of 195 children aged 6-17 years, with primary headache (migraine, or tension type headache) in 5 European paediatric hospitals. The control group is composed of 240 same-aged children attending with minor injuries during the same period - February 1st 2020 to December 1st 2020. A structured questionnaire identified a history of infantile regurgitation and other functional gastrointestinal disorders for case and control participants. The outcome wa

SUBMITTER: Lenglart L 

PROVIDER: S-EPMC8744028 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature

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