Associations of Performance-Based Functional Assessments and Adverse Outcomes in CKD.

ABSTRACT:

Background

The comparative utility of performance-based functional assessments in predicting adverse outcomes in CKD is unknown. To examine their relative utility, we examined three performance-based functional assessments in an observational cohort of patients with CKD.

Methods

We recruited 350 participants with stage II-V, predialysis CKD. Participants were administered three performance-based functional assessments: Short Physical Performance Battery (SPPB), Modified Mini-Mental Status Exam (M3SE), and Lawton Instrumental Activities of Daily Living (IADL). Scores were dichotomized on the basis of the median and combined into a summary score. Outcomes included 50% GFR reduction, ESKD, and death. We used Cox proportional hazards to assess the association of performance-base

SUBMITTER: Belkin MD 

PROVIDER: S-EPMC8791312 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature