An equation to estimate 24-hour total urine protein excretion rate in patients who underwent urine protein testing.

ABSTRACT:

Background

The urine protein-creatinine ratio (UPCR) in a spot first-morning urine sample is used to estimate 24-h urine proteinuria (24hUP) in patients who underwent urine protein testing. UPCR cannot be directly compared with 24-h proteinuria. Thus, an equation to estimate 24-h total protein excretion rate, using age, gender, and the UPCR may improve its bias and accuracy in patients who underwent urine protein testing.

Methods

We simultaneously measured 24-h urine protein and the same day's first-morning spot urine from patients with kidney disease. Generalized linear and no-linear models, using age, gender, and UPCR, were constructed to estimate for 24-h urine protein and the best model (NJ equation) was selected to estimated 24 hUP (e24hUP).

Results

A total of 54

SUBMITTER: Yang F 

PROVIDER: S-EPMC8801121 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature