Understanding the patient experience in hepatocellular carcinoma: a qualitative patient interview study.

ABSTRACT:

Purpose

This study aimed to elucidate the patient experience of hepatocellular carcinoma (HCC) to guide patient-centered outcome measurement in drug development.

Methods

Patients with HCC participated in qualitative interviews to elicit disease-related signs/symptoms and impacts, using discussion guides developed from literature searches and discussions with oncologists. Interview participants rated the disturbance of their experiences (0-10 scale). A conceptual model was developed and mapped against patient-reported outcome (PRO) instruments identified from database reviews.

Results

Interviews were conducted with 25 individuals with HCC (68% were men; median age: 63 years; 12% Barcelona clinic liver cancer (BCLC) stage A; 32% stage B; and 56% stage C) in the USA. Fif

SUBMITTER: Patel N 

PROVIDER: S-EPMC8847294 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature