P2RY14 downregulation in lung adenocarcinoma: a potential therapeutic target associated with immune infiltration.

ABSTRACT:

Background

The current study aimed to investigate the interrelation between P2RY14 and the prognosis of patients suffering from lung adenocarcinoma (LUAD) following surgery.

Methods

The differentially expressed gene (DEG) P2RY14 was screened by the Gene Expression Omnibus (GEO), The Cancer Genome Atlas (TCGA), and Immunology Database and Analysis Portal (ImmPort) databases. The relationship between P2RY14 and clinical data of LUAD was analyzed in TCGA and Kaplan-Meier (KM)-plotter databases. The association of P2RY14 with immune cells and immune-related expressed genes was analyzed in the Tumor Immune Estimation Resource (TIMER) database. A retrospective analysis of the 100 patients clinical data undergoing pulmonary adenocarcinoma surgery admitte

SUBMITTER: Xu T 

PROVIDER: S-EPMC8902120 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature