Outcome of transcatheter aortic valve replacement in bicuspid aortic valve stenosis with new-generation devices.

ABSTRACT:

Objectives

To compare device success and paravalvular leak rates of 3 new-generation transcatheter aortic valve replacement devices in patients with bicuspid aortic valve stenosis and to test their biomechanical performance in a computer-based simulation model of aortic root with increasing ellipticity.

Methods

This retrospective multicentre study included 56 bicuspid aortic valve patients undergoing transcatheter aortic valve replacement with new-generation devices: Lotus/Lotus Edge (N = 15; 27%), Evolut-R (N = 20; 36%) and ACURATE neo (N = 21; 37%). Three virtual simulation models of aortic root with increasing index of eccentricity (0-0.25-0.5) were implemented. Stress distribution, stent-root contact area and paravalvular orifice area were computed.

Results

Device

SUBMITTER: Gorla R 

PROVIDER: S-EPMC8906794 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature