Incorporating the mutational landscape of SARS-COV-2 variants and case-dependent vaccination rates into epidemic models.

ABSTRACT: Coronavirus Disease (COVID-19), which began as a small outbreak in Wuhan, China, in December 2019, became a global pandemic within months due to its high transmissibility. In the absence of pharmaceutical treatment, various non-pharmaceutical interventions (NPIs) to contain the spread of COVID-19 brought the entire world to a halt. After almost a year of seemingly returning to normalcy with the world's quickest vaccine development, the emergence of more infectious and vaccine resistant coronavirus variants is bringing the situation back to where it was a year ago. In the light of this new situation, we conducted a study to portray the possible scenarios based on the three key factors: impact of interventions (pharmaceutical and NPIs), vaccination rate, and vaccine efficacy. In our study, w

SUBMITTER: Chowdhury MM 

PROVIDER: S-EPMC8913432 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature