Use of nephrotoxic medications in adults with chronic kidney disease in Swedish and US routine care.

ABSTRACT:

Background

To characterize the use of nephrotoxic medications in patients with chronic kidney disease (CKD) Stages G3-5 in routine care.

Methods

We studied cohorts of adults with confirmed CKD G3-5 undergoing routine care from 1 January 2016 through 31 December 2018 in two health systems [Stockholm CREAtinine Measurements (SCREAM), Stockholm, Sweden (N = 57 880) and Geisinger, PA, USA (N = 16 255)]. We evaluated the proportion of patients receiving nephrotoxic medications within 1 year overall and by baseline kidney function, ranked main contributors and examined the association between receipt of nephrotoxic medication and age, sex, CKD G-stages comorbidities and provider awareness of the patient's CKD using multivariable logistic regression.

Results

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SUBMITTER: Bosi A 

PROVIDER: S-EPMC8922703 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature