Child serum metabolome and traffic-related air pollution exposure in pregnancy.

ABSTRACT:

Background

Maternal exposure to traffic-related air pollution during pregnancy has been shown to increase the risk of adverse birth outcomes and childhood disorders. High-resolution metabolomics (HRM) has previously been employed to identify metabolic responses to traffic-related air pollution in adults, including pregnant women. Thus far, no studies have examined metabolic effects of air pollution exposure in utero on neonates.

Methods

We retrieved stored neonatal blood spots for 241 children born in California between 1998 and 2007. These children were randomly selected from all California birth rolls to serve as birth-year matched controls for children with retinoblastoma identified from the California cancer registry for a case control study of childhood cancer. We estim

SUBMITTER: Ritz B 

PROVIDER: S-EPMC8926017 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature