A randomized trial of aerobic exercise in chronic kidney disease: Evidence for blunted cardiopulmonary adaptations.

ABSTRACT:

Background

Patients with chronic kidney disease have reduced cardiorespiratory fitness levels that contribute to mortality.

Objectives

The purpose of this study was to investigate the effects of aerobic exercise on cardiopulmonary function in patients with chronic kidney disease.

Methods

A total of 36 patients (mean [SD] estimated glomerular filtration rate 44 [12] ml/min/1.73m²) were randomly allocated to an exercise training or a control arm over 12 weeks. The exercise training group performed aerobic exercise for 45min 3 times/week at 65% to 80% heart rate reserve. The control group received routine care. Outcome measures were assessed at baseline and 12 weeks. Cardiopulmonary exercise testing was performed on a cycle ergometer with workload increased by

SUBMITTER: Kirkman DL 

PROVIDER: S-EPMC8943710 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature