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ABSTRACT: Objective
To compare old patients hospitalized in ICU for respiratory distress due to COVID-19 with old patients hospitalized in ICU for a non-COVID-19-related reason in terms of autonomy and quality of life.Design
Comparison of two prospective multi-centric studies.Setting
This study was based on two prospective multi-centric studies, the Senior-COVID-Rea cohort (COVID-19-diagnosed ICU-admitted patients aged over 60) and the FRAGIREA cohort (ICU-admitted patients aged over 70).Patients
We included herein the patients from both cohorts who had been evaluated at day 180 after admission (ADL score and quality of life).Interventions
None.Measurements and main results
A total of 93 COVID-19 patients and 185 control-ICU patients were included. Both groups were not balanced on age, body mass index, mechanical ventilation, length of ICU stay, and ADL and SAPS II scores. We modeled with ordered logistic regression the influence of COVID-19 on the quality of life and the ADL score. After adjustment on these factors, we observed COVID-19 patients were less likely to have a loss of usual activities (aOR [95% CI] 0.47 [0.23; 0.94]), a loss of mobility (aOR [95% CI] 0.30 [0.14; 0.63]), and a loss of ADL score (aOR [95% CI] 0.30 [0.14; 0.63]). On day 180, 52 (56%) COVID-19 patients presented signs of dyspnea, 37 (40%) still used analgesics, 17 (18%) used anxiolytics, and 14 (13%) used antidepressant.Conclusions
COVID-19-related ICU stay was not associated with a lower quality of life or lower autonomy compared to non-COVID-19-related ICU stay.
SUBMITTER: Thiolliere F
PROVIDER: S-EPMC8978758 | biostudies-literature | 2022 Apr
REPOSITORIES: biostudies-literature
Thiolliere Fabrice F Falandry Claire C Allaouchiche Bernard B Geoffray Victor V Bitker Laurent L Reignier Jean J Abraham Paul P Malaquin Stephanie S Balança Baptiste B Boyer Hélène H Seguin Philippe P Guichon Céline C Simon Marie M Friggeri Arnaud A Vacheron Charles-Hervé CH
Critical care (London, England) 20220404 1
<h4>Objective</h4>To compare old patients hospitalized in ICU for respiratory distress due to COVID-19 with old patients hospitalized in ICU for a non-COVID-19-related reason in terms of autonomy and quality of life.<h4>Design</h4>Comparison of two prospective multi-centric studies.<h4>Setting</h4>This study was based on two prospective multi-centric studies, the Senior-COVID-Rea cohort (COVID-19-diagnosed ICU-admitted patients aged over 60) and the FRAGIREA cohort (ICU-admitted patients aged ov ...[more]