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Incidence of headache after COVID-19 vaccination in patients with history of headache: A cross-sectional study.


ABSTRACT:

Background

Headache is an adverse event of coronavirus 2019 (COVID-19) vaccination. Whether patients with history of headache suffer more from vaccination-induced headaches is unknown. We aimed to uncover if headache patients develop more headaches after COVID-19 mRNA vaccination than healthy controls.

Methods

We performed a questionnaire survey for nursing staff in our hospital from April to May 2021. Based on baseline characteristics, we divided the participants into migraine, non-migrainous headache, and healthy control, and examined the occurrence and features of headache after COVID-19 vaccinations.

Results

We included 171 participants (15.2% migraine and 24.6% non-migrainous headache). Headache incidence after vaccinations was significantly higher in the migraine (69.2%) and non-migrainous headache (71.4%) groups than in the healthy control (37.9%) group. The incidence of headaches was significantly higher after the second dose compared to the first (45.6% vs. 20.5%).

Conclusion

Migraineurs and non-migrainous headache participants developed more headaches compared to the healthy controls after COVID-19 vaccination.

SUBMITTER: Sekiguchi K 

PROVIDER: S-EPMC8988452 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature

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Publications

Incidence of headache after COVID-19 vaccination in patients with history of headache: A cross-sectional study.

Sekiguchi Koji K   Watanabe Narumi N   Miyazaki Naoki N   Ishizuchi Kei K   Iba Chisato C   Tagashira Yu Y   Uno Shunsuke S   Shibata Mamoru M   Hasegawa Naoki N   Takemura Ryo R   Nakahara Jin J   Takizawa Tsubasa T  

Cephalalgia : an international journal of headache 20210818 3


<h4>Background</h4>Headache is an adverse event of coronavirus 2019 (COVID-19) vaccination. Whether patients with history of headache suffer more from vaccination-induced headaches is unknown. We aimed to uncover if headache patients develop more headaches after COVID-19 mRNA vaccination than healthy controls.<h4>Methods</h4>We performed a questionnaire survey for nursing staff in our hospital from April to May 2021. Based on baseline characteristics, we divided the participants into migraine, n  ...[more]

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