Rapidly improving acute respiratory distress syndrome in COVID-19: a multi-centre observational study.

ABSTRACT:

Background

Before the pandemic of coronavirus disease (COVID-19), rapidly improving acute respiratory distress syndrome (ARDS), mostly defined by early extubation, had been recognized as an increasingly prevalent subphenotype (making up 15-24% of all ARDS cases), associated with good prognosis (10% mortality in ARDSNet trials). We attempted to determine the prevalence and prognosis of rapidly improving ARDS and of persistent severe ARDS related to COVID-19.

Methods

We included consecutive patients with COVID-19 receiving invasive mechanical ventilation in three intensive care units (ICU) during the second pandemic wave in Greece. We defined rapidly improving ARDS as extubation or a partial pressure of arterial oxygen to fraction of inspired oxygen ratio (PaO₂:FiO<

SUBMITTER: Gavrielatou E 

PROVIDER: S-EPMC9008400 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature