Associations between vitamin D levels and glucose metabolism markers among pregnant women and their infants in Puerto Rico.
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ABSTRACT: Introduction
Objectives: low vitamin D during pregnancy is common and could adversely affect health outcomes. This study evaluated vitamin D status during pregnancy and early in life, and its association with glucose metabolism. Methods: maternal serum 25(OH)D, glucose, and insulin levels were measured longitudinally during pregnancy in Hispanic women with overweight/obesity (n = 31) and their infants at birth and 4 months. Results: insulin and HOMA-IR levels were higher among women with vitamin D below adequate levels compared to those with adequate levels in pregnancy (p < 0.05). Late in pregnancy, as vitamin D increased by one unit (ng/mL), insulin decreased by 0.44 units and HOMA-IR by 0.09 units. Maternal vitamin D late in pregnancy was correlated with infant vitamin D levels at birth (r = 0.89; p < 0.01) and 4 months (r = 0.9; p = 0.04), and with glucose (r = 0.79; p = 0.03) and insulin (r = 0.83; p = 0.04) at 4 months. Conclusion: maternal vitamin D status was associated with maternal and infant glucose metabolism in this sample.
SUBMITTER: Palacios C
PROVIDER: S-EPMC9015214 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Publications
Associations between vitamin D levels and glucose metabolism markers among pregnant women and their infants in Puerto Rico.
Palacios Cristina C Trak-Fellermeier Maria Angelica MA Melendez Marytere M Campos Maribel M Pomeroy Jeremy J Guo Kai K Franks Paul W PW Joshipura Kaumudi K
Nutricion hospitalaria 20211201 6
<h4>Introduction</h4>Objectives: low vitamin D during pregnancy is common and could adversely affect health outcomes. This study evaluated vitamin D status during pregnancy and early in life, and its association with glucose metabolism. Methods: maternal serum 25(OH)D, glucose, and insulin levels were measured longitudinally during pregnancy in Hispanic women with overweight/obesity (n = 31) and their infants at birth and 4 months. Results: insulin and HOMA-IR levels were higher among women with ...[more]
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