Postvaccination COVID-19 infection is associated with reduced mortality in patients with cirrhosis.

ABSTRACT:

Background and aims

Patients develop breakthrough COVID-19 infection despite vaccination. The aim of this study was to identify outcomes in patients with cirrhosis who developed postvaccination COVID-19.

Methods

We performed a retrospective cohort study among US veterans with cirrhosis and postvaccination or unvaccinated COVID-19. Patients were considered fully vaccinated if COVID-19 was diagnosed 14 days after the second dose of either the Pfizer BNT162b2, the Moderna 1273-mRNA, or the single-dose Janssen Ad.26.COV2.S vaccines and partially vaccinated if COVID-19 was diagnosed 7 days after the first dose of any vaccine but prior to full vaccination. We investigated the association of postvaccination COVID-19 with mortality.

Results

We identified 3242 unvaccinated and

SUBMITTER: John BV 

PROVIDER: S-EPMC9015228 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature