Temporal trends in associations between severe mental illness and risk of cardiovascular disease: A systematic review and meta-analysis.

ABSTRACT:

Background

Severe mental illness (SMI; schizophrenia, bipolar disorders (BDs), and other nonorganic psychoses) is associated with increased risk of cardiovascular disease (CVD) and CVD-related mortality. To date, no systematic review has investigated changes in population level CVD-related mortality over calendar time. It is unclear if this relationship has changed over time in higher-income countries with changing treatments.

Methods and findings

To address this gap, a systematic review was conducted, to assess the association between SMI and CVD including temporal change. Seven databases were searched (last: November 30, 2021) for cohort or case-control studies lasting ≥1 year, comparing frequency of CVD mortality or incidence in high-income countries between people with v

SUBMITTER: Lambert AM 

PROVIDER: S-EPMC9017899 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature