Insights on Distinct Left Atrial Remodeling Between Atrial Fibrillation and Heart Failure With Preserved Ejection Fraction.

ABSTRACT:

Background

Heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) commonly coexist with overlapping pathophysiology like left atrial (LA) remodeling, which might differ given different underlying mechanisms.

Objectives

We sought to investigate the different patterns of LA wall remodeling in AF vs. HFpEF.

Methods

We compared LA wall characteristics including wall volume (LAWV), wall thickness (LAWT), and wall thickness heterogeneity (LAWT[SD]) and LA structure, function among the controls (without AF or HFpEF, n = 115), HFpEF alone (n = 59), AF alone (n = 37), and HFpEF+AF (n = 38) groups using multi-detector computed tomography and echocardiography.

Results

LA wall remodeling was most predominant and peak

SUBMITTER: Kuo JY 

PROVIDER: S-EPMC9086706 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature