Investigation of dual-bend serpentine/spiral waveguides coupled to a microchannel system for competent, evanescent-wave-absorption-based, on-chip, biological-/chemical-sensing applications.

ABSTRACT: U or C-shaped waveguides, coupled to analyte microchannels, have been shown to be very responsive to evanescent-wave-absorption-based sensing. However, due to only having a single C-bend length, for analyte interaction in earlier devices, there was always an opportunity to advance their evanescent-absorbance sensitivity, by including multiple C-bend structures (interfaced with the analyte microchannel system) in the device design. To achieve this objective, two different types of waveguide probes (having a different orientation of two C-bends), i.e. S-bend and spiral-bend, were theoretically analyzed and further, experimentally tested for their comparative sensitivity to evanescent wave absorption, in this pioneering study. A novel single-step fabrication procedure (using an SU-8 ph

SUBMITTER: Prabhakar A 

PROVIDER: S-EPMC9088425 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature