An evolutionary gap in primate default mode network organization.
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ABSTRACT:
SUBMITTER: Garin CM
PROVIDER: S-EPMC9088817 | biostudies-literature | 2022 Apr
REPOSITORIES: biostudies-literature
Publications
An evolutionary gap in primate default mode network organization.
Garin Clément M CM Hori Yuki Y Everling Stefan S Whitlow Christopher T CT Calabro Finnegan J FJ Luna Beatriz B Froesel Mathilda M Gacoin Maëva M Ben Hamed Suliann S Dhenain Marc M Constantinidis Christos C
Cell reports 20220401 2
The human default mode network (DMN) is engaged at rest and in cognitive states such as self-directed thoughts. Interconnected homologous cortical areas in primates constitute a network considered as the equivalent. Here, based on a cross-species comparison of the DMN between humans and non-hominoid primates (macaques, marmosets, and mouse lemurs), we report major dissimilarities in connectivity profiles. Most importantly, the medial prefrontal cortex (mPFC) of non-hominoid primates is poorly en ...[more]
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