Topology and Sequence-Dependent Micellization and Phase Separation of Pluronic L35, L64, 10R5, and 17R4: Effects of Cyclization and the Chain Ends.

ABSTRACT: The topology effects of cyclization on thermal phase transition behaviors were investigated for a series of amphiphilic Pluronic copolymers of both hydrophilic-hydrophobic-hydrophilic and hydrophobic-hydrophilic-hydrophobic block sequences. The dye solubilization measurements revealed the lowered critical micelle temperatures (T_CMT) along with the decreased micellization enthalpy (ΔH_mic) and entropy (ΔS_mic) for the cyclized species. Furthermore, the transmittance and dynamic light scattering (DLS) measurements indicated a block sequence-dependent effect on the clouding phenomena, where a profound decrease in cloud point (T_c) was only found for the copolymers with a hydrophilic-hydrophobic-hydrophilic block sequence. Th

SUBMITTER: Watanabe T 

PROVIDER: S-EPMC9105568 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature