Inter- and intra-individual variability of active glucagon-like peptide 1 among healthy adults.

ABSTRACT:

Objective

To determine whether sex, age, and body mass index are correlated with active glucagon-like-peptide 1 concentrations and to investigate glucagon-like-peptide 1 reproducibility during repeated oral glucose tolerance tests.

Methods

Sixty-one healthy volunteers underwent four 2-hour repeated oral glucose tolerance tests approximately 1 week apart. Because this randomized same-subject crossover trial was designed to investigate effects of non-nutritive sweeteners, participants received 355 mL (12 ounces) of water or a beverage containing non-nutritive sweeteners 10 minutes prior to each oral glucose tolerance test. Blood samples were collected 10 minutes before, and 0, 10, 20, 30, 60, 90, and 120 minutes following ingestion of 75 grams of glucose.

Results

Basal

SUBMITTER: Sylvetsky AC 

PROVIDER: S-EPMC9119643 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature