Olfactory adaptation: recordings from the human olfactory epithelium.

ABSTRACT:

Purpose

Olfactory adaptation is a peripheral (at the epithelium level) or a central (at the brain level) mechanism resulting from repeated or prolonged odorous exposure that can induce a perceptual decrease. The aim of this study was to assess whether a peripheral adaptation occurs when an odor is repeated ten times. Moreover, the specificity of the peripheral adaptation to the nature of the odorant was investigated.

Methods

Four odorants (eugenol, manzanate, ISO E Super and phenylethanol) were presented using precisely controlled air-dilution olfactometry. They differed in terms of their physicochemical properties. Electrophysiological recordings were made at the level of the olfactory mucosa, the so-called electro-olfactogram (EOG). Thirty-five right-handed participants we

SUBMITTER: Mignot C 

PROVIDER: S-EPMC9130158 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature