Safety of Minimizing Intensity of Follow-up on Active Surveillance for Clinical Stage I Testicular Germ Cell Tumors.

ABSTRACT:

Background

We have recommended active surveillance as the preferred management option for clinical stage I (CSI) testicular germ cell tumors (GCTs) since 1980. Over time, the recommended intensity of surveillance has decreased; however, the impact on relapse detection has not been investigated.

Objective

To examine relapse rate, time to relapse, extent of disease, and burden of treatment at relapse across decreasing surveillance intensity over time.

Design setting and participants

CSI GCT patients under active surveillance from 1981 to 2021 were included in this study.

Outcome measurements and statistical analysis

Through four major iterations in both nonseminomatous (NSGCT) and seminoma surveillance schedules, visit frequency, blood testing, and imaging have b

SUBMITTER: Gariscsak PJ 

PROVIDER: S-EPMC9142749 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature