Ontology highlight
ABSTRACT:
SUBMITTER: Wang X
PROVIDER: S-EPMC9170380 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
RSC advances 20220606 26
A metal- and base-free 5-<i>endo</i>-trig sulfonylative cyclization between 1,5-dienes, aryldiazonium salts and SO<sub>2</sub> (from SOgen) is presented. This method could successfully produce sulfonylated pyrrolin-2-ones in one pot with excellent regioselectivity and good-to-excellent yields. This strategy features mild reaction conditions and broad substrate scope. Moreover, a scale-up reaction and three synthetic applications demonstrate the practicality of this method. Lastly, control experi ...[more]