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Utility and Applicability of Rapid Diagnostic Testing in Antimicrobial Stewardship in the Asia-Pacific Region: A Delphi Consensus.


ABSTRACT: Rapid diagnostic tests (RDTs) facilitate fast and accurate identification of infectious disease microorganisms and are a valuable component of multimodal antimicrobial stewardship (AMS) programs but are currently underutilized in the Asia-Pacific region. An experienced group of infectious diseases clinicians, clinical microbiologists, and a clinical pharmacist used a modified Delphi consensus approach to construct 10 statements, aiming to optimize the utility and applicability of infection-related RDTs for AMS in the Asia-Pacific region. They provide guidance on definition, types, optimal deployment, measuring effectiveness, and overcoming key challenges. The Grading of Recommendations Assessment, Development, and Evaluation system was applied to indicate the strength of the recommendation and the quality of the underlying evidence. Given the diversity of the Asia-Pacific region, the trajectory of RDT development will vary widely; the collection of local data should be prioritized to allow realization and optimization of the full benefits of RDTs in AMS.

SUBMITTER: Apisarnthanarak A 

PROVIDER: S-EPMC9187322 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature

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Utility and Applicability of Rapid Diagnostic Testing in Antimicrobial Stewardship in the Asia-Pacific Region: A Delphi Consensus.

Apisarnthanarak Anucha A   Bin Kim Hong H   Moore Luke S P LSP   Xiao Yonghong Y   Singh Sanjeev S   Doi Yohei Y   Kwa Andrea Lay-Hoon AL   Ponnampalavanar Sasheela Sri La Sri SSS   Cao Qing Q   Kim Shin-Woo SW   Lee Hyukmin H   Santanirand Pitak P  

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20220601 11


Rapid diagnostic tests (RDTs) facilitate fast and accurate identification of infectious disease microorganisms and are a valuable component of multimodal antimicrobial stewardship (AMS) programs but are currently underutilized in the Asia-Pacific region. An experienced group of infectious diseases clinicians, clinical microbiologists, and a clinical pharmacist used a modified Delphi consensus approach to construct 10 statements, aiming to optimize the utility and applicability of infection-relat  ...[more]

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