Seawater immersion exacerbates the pathological changes caused by incisive corneal injury in rabbit eyes.

ABSTRACT:

Background

Seawater immersion complicates injuries suffered during maritime conflicts and eye injury is one of most common injuries on the battlefield. This study aimed to delineate the pathophysiological changes in the cornea after corneal injury combined with seawater immersion.

Methods

The left eye of New Zealand White rabbits was injured with firecracker and a 3-mm long whole-layer incision in the center of the cornea parallel to the corneal limbus, followed by seawater immersion. The right eye was used as a control. The histology of the cornea and the inflammatory cytokine/chemokine levels in the aqueous humor were examined on days 1 and 7 after injury. The protein levels of aquaporin 1, 3, and 5 were assessed by immunohistochemical staining 7 days after injury. The exp

SUBMITTER: Wang YF 

PROVIDER: S-EPMC9201191 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature