Effects of Biomimetic Micropatterned Surfaces on the Adhesion and Morphology of Cervical Cancer Cells.

ABSTRACT: It has been demonstrated that micropatterned surfaces have an important influence on modulating cellular behavior. In recent years, with the rapid development of microfabrication techniques and in-depth study of nature, an increasing number of patterned structures imitating natural organisms have been successfully fabricated and widely evaluated. However, there are only a few reports about biomimetic patterned microstructures in biologically related fields. In our work, micropatterned polydimethylsiloxane (PDMS) was fabricated by mimicking the surface microstructures of natural Trifolium and Parthenocissus tricuspidata leaves using the template duplication method. The interactions between the two types of biomimetic micro-PDMS surfaces and two kinds of human cervical cancer cells (H

SUBMITTER: Zhang X 

PROVIDER: S-EPMC9202008 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature