The effects of mouthwashes in human gingiva epithelial progenitor (HGEPp) cells.

ABSTRACT:

Objectives

The gingiva epithelium accounts for a significant proportion of the surface around the tooth. An inflammatory reaction occurs in the presence of bacterial biofilm, adhesion is reduced, and the depth of the sulcus gingivalis increases. The most common antiseptic agents in oral rinses are chlorhexidine digluconate (CHX) and cetylpyridinium chloride. We examined long-lasting effects of residual concentrations of eight commercially available rinses. Our main goals were (i) to analyze the effect of different chemical compositions on cell proliferation, (ii) to examine apoptosis, and (iii) cell morphology on human epithelial progenitor cell line (HGEPp).

Materials and methods

Cell proliferation was measured in a real-time system (0-48 h) by impedimetry (xCELLigence). Ap

SUBMITTER: Kohidai Z 

PROVIDER: S-EPMC9203393 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature