Hierarchical Symptom Components in Early Psychosis.

ABSTRACT:

Background and hypothesis

Quantitative models of psychopathology can empirically guide subclassification of heterogeneous clinical presentations such as psychosis; they are particularly well-equipped to capture the nuanced symptomatology observed in first-episode psychosis. As well, components may be better aligned with biological variables. The current study sought to confirm and extend knowledge of the hierarchical structure of psychosis symptoms in first-episode psychosis. Based on past hierarchical work, we hypothesized that a 4 component level would be most closely associated with longitudinal disability.

Study design

Participants with early-stage psychosis (N = 370) underwent clinical assessment with the scale for the assessment of positive symptoms (SAPS), scale for a

SUBMITTER: Longenecker JM 

PROVIDER: S-EPMC9212103 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature