Bacterial drug-resistance patterns and genetic diversity of bacteria-associated bacteriuria in diabetic patients in Ghana.

ABSTRACT:

Objectives

Our study aimed to determine the etiology of urinary tract infections (UTIs), resistance profiles of isolated bacteria, and virulence factors of Escherichia coli associated with bacteriuria in diabetic patients in Ghana.

Methods

Midstream urine samples from 982 diabetic patients were tested for uropathogens at the National Diabetes Management and Research Centre in Ghana, using standard bacteriological methods, with antibiogram testing of the isolates using the Kirby-Bauer disk diffusion, as per CLSI guidelines. Polymerase chain reaction (PCR) was used to investigate the phylogenetic groupings and virulence factor (VF) genes of isolated E. coli.

Results

The overall prevalence of UTIs was 9.2%, and the main uropathogens were Klebsiella s

SUBMITTER: Forson AO 

PROVIDER: S-EPMC9216422 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature