Characterization of the First Carbapenem-Resistant Pseudocitrobacter faecalis Harboring bla_OXA-181 in China.

ABSTRACT: With the wide use of carbapenems, carbapenem-resistant Enterobacterales have been increasingly reported worldwide. In this study, one bla_OXA-181-positive Pseudocitrobacter faecalis strain was isolated from the blood culture of a patient with a bloodstream infection in China, which was its first clinical report outside Pakistan. Species identification of P. faecalis was initially performed using MALDI-TOF/MS and further confirmed by 16S rRNA gene and housekeeping gene sequencing. The antimicrobial susceptibility testing was determined through the broth microdilution method, and their clonal relationship was analyzed by pulsed-field gel electrophoresis. To study the transmission and genetic structure of the bla_OXA-181 gene, a transform

SUBMITTER: Shi Q 

PROVIDER: S-EPMC9220048 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature