Dataset Information

Brief dispersion of a putative B.1.1.28-derived SARS-CoV-2 lineage harboring additional N234P and E471Q spike protein mutations in individuals crossing the Argentina-Brazil border.

ABSTRACT:

Background

SARS-CoV-2, the virus that causes COVID-19, is constantly mutating, leading to new variants that culminate in a temporal lineages fluctuation. B.1.1.28 lineage has been evolving in Brazil since February 2020 and originated P.1 (VOC), P.2 (VOI) and other P.Xs proposed as new variants.

Methods and results

In this study, through the Illumina platform, we performed the whole-genome sequencing of 26 positive samples of SARS-CoV-2. Employing variant calling analysis on FASTQ reads and phylogenetic inference, we report a brief dispersion of a potentially new B.1.1.28-derived variant detected between 2021 May and June in individuals crossing the border between Brazil and Argentina, and local spread to inpatients from hospitals at the Rio Grande do Sul state capital (Porto Alegre). Besides, the Rio Grande do Sul State SARS-CoV-2 genomic epidemiological data was analyzed and showed an important B.1.1.28 peak in RS at the same period (May-June), even in the presence of a major Gamma wave.

Conclusions

The emergence of a putative B.1.1.28-derived lineage was identified in travelers crossing Brazil-Argentina border representing an important peak of B.1.1.28 in RS State with a decreased in Gamma variant frequency in the same period of time.

SUBMITTER: Soares da Silva M

PROVIDER: S-EPMC9221948 | biostudies-literature | 2022 Sep-Oct

REPOSITORIES: biostudies-literature

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Publications

Brief dispersion of a putative B.1.1.28-derived SARS-CoV-2 lineage harboring additional N234P and E471Q spike protein mutations in individuals crossing the Argentina-Brazil border.

Soares da Silva Mariana M Gularte Juliana Schons JS Demoliner Meriane M Hansen Alana Witt AW Heldt Fágner Henrique FH Filippi Micheli M Luckmann Cristiane Borba CB Malayhka de Abreu Góes Pereira Vyctoria V de Almeida Vaucher Rodrigo R Barboza Victor Dos Santos VDS Giongo Janice Luehring JL Rosa Raquel Borba RB Tarouco da Rocha Evelise E Goulart Bruno Kilpp BK Fernandes Fernanda Dos Santos FDS Pinto Juliana Maciel JM Bolzan Leandro Pergher LP Medeiros Frescura Duarte Marta Maria MM Weber Matheus Nunes MN Rodrigues de Almeida Paula P Fleck Juliane Deise JD Spilki Fernando Rosado FR

Travel medicine and infectious disease 20220623

<h4>Background</h4>SARS-CoV-2, the virus that causes COVID-19, is constantly mutating, leading to new variants that culminate in a temporal lineages fluctuation. B.1.1.28 lineage has been evolving in Brazil since February 2020 and originated P.1 (VOC), P.2 (VOI) and other P.Xs proposed as new variants.<h4>Methods and results</h4>In this study, through the Illumina platform, we performed the whole-genome sequencing of 26 positive samples of SARS-CoV-2. Employing variant calling analysis on FASTQ ...[more]

PMID: 35753659

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Dataset Information

Brief dispersion of a putative B.1.1.28-derived SARS-CoV-2 lineage harboring additional N234P and E471Q spike protein mutations in individuals crossing the Argentina-Brazil border.

Background

Methods and results

Conclusions

Publications

Brief dispersion of a putative B.1.1.28-derived SARS-CoV-2 lineage harboring additional N234P and E471Q spike protein mutations in individuals crossing the Argentina-Brazil border.

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