A roadmap for the generation of benchmarking resources for antimicrobial resistance detection using next generation sequencing.

ABSTRACT: Next Generation Sequencing technologies significantly impact the field of Antimicrobial Resistance (AMR) detection and monitoring, with immediate uses in diagnosis and risk assessment. For this application and in general, considerable challenges remain in demonstrating sufficient trust to act upon the meaningful information produced from raw data, partly because of the reliance on bioinformatics pipelines, which can produce different results and therefore lead to different interpretations. With the constant evolution of the field, it is difficult to identify, harmonise and recommend specific methods for large-scale implementations over time. In this article, we propose to address this challenge through establishing a transparent, performance-based, evaluation approach to provide flexibilit

SUBMITTER: Petrillo M 

PROVIDER: S-EPMC9243550 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature