Characterization of NDM-5 Carbapenemase-Encoding Gene (bla _NDM-5) - Positive Multidrug Resistant Commensal Escherichia coli from Diarrheal Patients.

ABSTRACT:

Purpose

The multidrug resistance Enterobacteriaceae cause many serious infections resulting in prolonged hospitalization, increased treatment charges and mortality rate. In this study, we characterized bla _NDM-5-positive multidrug resistance commensal Escherichia coli (CE) isolated from diarrheal patients in Kolkata, India.

Methods

Three CE strains were isolated from diarrheal stools, which were negative for different pathogroups of diarrheagenic E. coli (DEC). The presence of carbapenemases encoding genes and other antimicrobial resistance genes (ARGs) was detected using PCR. The genetic arrangement adjoining bla _NDM-5 was investigated by plasmid genome sequencing. The genetic relatedness of the strains was determined by pul

SUBMITTER: Chowdhury G 

PROVIDER: S-EPMC9275505 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature