A new magnetic resonance imaging tumour response grading scheme for locally advanced rectal cancer.

ABSTRACT:

Background

The potential of using magnetic resonance image tumour-regression grading (MRI-TRG) system to predict pathological TRG is debatable for locally advanced rectal cancer treated by neoadjuvant radiochemotherapy.

Methods

Referring to the American Joint Committee on Cancer/College of American Pathologists (AJCC/CAP) TRG classification scheme, a new four-category MRI-TRG system based on the volumetric analysis of the residual tumour and radiochemotherapy induced anorectal fibrosis was established. The agreement between them was evaluated by Kendall's tau-b test, while Kaplan-Meier analysis was used to calculate survival outcomes.

Results

In total, 1033 patients were included. Good agreement between MRI-TRG and AJCC/CAP TRG classifications was observed (k = 0.671)

SUBMITTER: Pang X 

PROVIDER: S-EPMC9296509 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature