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Cobalt-Catalyzed Dehydrogenative C-H Silylation of Alkynylsilanes.

ABSTRACT: Herein, we report that a cobalt catalyst permits the general synthesis of substituted alkynylsilanes through dehydrogenative coupling of alkynylsilanes and hydrosilanes. Several silylated alkynes, including di- and trisubstituted ones, were prepared in a one-step procedure. Thirty-seven compounds were synthesized for the first time by applying our catalyst system. The alkynylsilanes bearing hydrosilyl moieties provide an opportunity for further functionalization (e. g., hydrosilylation). The use of primary silanes as substrates and precatalyst activators permits the use of inexpensive and easily accessible 3d metal precatalysts, and avoids the presence of additional activators.

SUBMITTER: Stachowiak H

PROVIDER: S-EPMC9299208 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature

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Cobalt-Catalyzed Dehydrogenative C-H Silylation of Alkynylsilanes.

Stachowiak Hanna H Kuciński Krzysztof K Kallmeier Fabian F Kempe Rhett R Hreczycho Grzegorz G

Chemistry (Weinheim an der Bergstrasse, Germany) 20211108 1

Herein, we report that a cobalt catalyst permits the general synthesis of substituted alkynylsilanes through dehydrogenative coupling of alkynylsilanes and hydrosilanes. Several silylated alkynes, including di- and trisubstituted ones, were prepared in a one-step procedure. Thirty-seven compounds were synthesized for the first time by applying our catalyst system. The alkynylsilanes bearing hydrosilyl moieties provide an opportunity for further functionalization (e. g., hydrosilylation). The use ...[more]

PMID: 34634167

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