Pathological Findings Associated With SARS-CoV-2 on Postmortem Core Biopsies: Correlation With Clinical Presentation and Disease Course.

ABSTRACT:

Background

Autopsies can shed light on the pathogenesis of new and emerging diseases.

Aim

To describe needle core necropsy findings of the lung, heart, and liver in decedents with COVID-19.

Material

Cross-sectional study of needle core necropsies in patients who died with virologically confirmed COVID-19. Histopathological analyses were performed, and clinical data and patient course evaluated.

Results

Chest core necropsies were performed in 71 decedents with a median age of 81 years (range 52-97); 47 (65.3%) were men. The median interval from symptoms onset to death was 17.5 days (range 1-84). Samples of lung (n = 62, 87.3%), heart (n = 48, 67.6%) and liver (n = 39, 54.9%) were obtained. Fifty-one lung samples (82.3%) were abnormal: 19 (30

SUBMITTER: Ramos-Rincon JM 

PROVIDER: S-EPMC9301383 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature