Consequences of cervical pessary for subsequent pregnancy: follow-up of randomized clinical trial (ProTWIN).

ABSTRACT:

Objective

To evaluate the effect of cervical pessary, as a strategy to prevent preterm birth (PTB), on the outcome of subsequent pregnancy and maternal quality of life 4 years after the index twin pregnancy.

Methods

Between 2009 and 2012, the ProTWIN trial randomized women with a multiple pregnancy to pessary use vs standard care for the prevention of PTB. The trial showed no benefit in unselected women with a twin pregnancy, but showed a 60% reduction in poor perinatal outcomes in favor of the pessary group in the subgroup of women with a mid-trimester short cervix (cervical length < 38 mm). All women were invited to participate in a follow-up study 4 years after their participation in the ProTWIN trial. In this follow-up study, maternal quality of life was assessed using t

SUBMITTER: van Limburg Stirum EVJ 

PROVIDER: S-EPMC9328140 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature