The SARS-CoV-2 targeted human RNA binding proteins network biology to investigate COVID-19 associated manifestations.

ABSTRACT: The global coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 virus has had unprecedented social and economic ramifications. Identifying targets for drug repurposing could be an effective means to present new and fast treatments. Furthermore, the risk of morbidity and mortality from COVID-19 goes up when there are coexisting medical conditions, however, the underlying mechanisms remain unclear. In the current study, we have adopted a network-based systems biology approach to investigate the RNA binding proteins (RBPs)-based molecular interplay between COVID-19, various human cancers, and neurological disorders. The network based on RBPs commonly involved in the three disease conditions consisted of nine RBPs connecting 10 different cancer types, 22 brain disorders, and C

SUBMITTER: Prasad K 

PROVIDER: S-EPMC9328843 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature