Serum levels of apolipoprotein A-I and E are associated with postoperative delirium: A post hoc analysis.

ABSTRACT: Postoperative delirium is a common complication for elderly patients. Detection of phosphorylated neurofilament heavy subunit in the serum reflects axonal damage with postoperative delirium. Although it has been implicated that serum apolipoprotein levels might be associated with senile cognitive disorder, its role in the development of delirium has not been fully investigated. This study examined the association of apolipoproteins with delirium after surgery. This was a post hoc analysis of 117 patients who participated in a prospective observational study of delirium in patients undergoing cancer surgery. Patients were clinically assessed for delirium within the first 5 days of surgery. Serum levels of apolipoprotein A-I, B, and E were measured on postoperative day 3. Forty-one patients

SUBMITTER: Mietani K 

PROVIDER: S-EPMC9333508 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature