Consanguineous Marriage and Early Pregnancy Loss in Rural to Peri-Urban India.

ABSTRACT:

Background

Consanguineous marriage (CM) has been linked to spontaneous abortion (SAB), although studies have largely been cross-sectional and likely underestimated early loss. We aimed to determine the relationships between CM and SAB in a prospective pregnancy cohort study in Telangana State, India.

Methods

Data from 661 participants aged 15-35 years in the Longitudinal Indian Family hEalth (LIFE) study actively followed for pregnancy and pregnancy loss were analyzed. SAB was classified as early (< 8) or late (8-22) weeks gestation. We used logistic regression to model the relationships between CM, defined by first-cousin marriage, and SAB, adjusted for maternal age.

Results

Women in CM were at a modestly increased risk of any (OR_adj 1.15, 95% CI 0.69, 1.9

SUBMITTER: Robertson JM 

PROVIDER: S-EPMC9339451 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature