Outcomes of asymptomatic recombinant tissue plasminogen activator associated intracranial hemorrhage.

ABSTRACT:

Background

Intracranial hemorrhage (ICH) is the most devastating complication of recombinant tissue plasminogen activator (rtPA) treatment in acute ischemic stroke patients. Data on rtPA-associated asymptomatic ICH (aICH) are limited.

Objectives

To determine the incidence, risk factors, characteristics, management, and clinical outcome of rtPA-associated aICH.

Methods

The data were retrieved from the Chiang Mai University Hospital Stroke Registry between 1995 and 2019. Consecutive ischemic stroke patients were included if they were 18 or older and received rtPA. Study outcomes were the incidence and characteristics of aICH, management, 90-day modified Rankin scale (mRS), National Institute of Health Stroke Scale (NIHSS), Barthel index, and all-cause mortality.

Resu

SUBMITTER: Teekaput C 

PROVIDER: S-EPMC9342748 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature