Cluster analysis unveils a severe persistent respiratory impairment phenotype 3-months after severe COVID-19.

ABSTRACT:

Background

The mid-term respiratory sequelae in survivors of severe COVID-19 appear highly heterogeneous. In addition, factors associated with respiratory sequelae are not known. In this monocentric prospective study, we performed a multidisciplinary assessment for respiratory and muscular impairment and psychological distress 3 months after severe COVID-19. We analysed factors associated with severe persistent respiratory impairment, amongst demographic, COVID-19 severity, and 3-month assessment.

Methods

Patients with severe SARS-CoV-2 pneumonia requiring ≥ 4L/min were included for a systematic 3-month visit, including respiratory assessment (symptoms, lung function, CT scan), muscular evaluation (body composition, physical function and activity, disability), psychopatholog

SUBMITTER: Perotin JM 

PROVIDER: S-EPMC9344257 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature