Implementation of functional imaging using ¹¹C-methionine PET-CT co-registered with MRI for advanced surgical planning and decision making in prolactinoma surgery.

ABSTRACT:

Purpose

To report the first experience of our multidisciplinary team with functional imaging using ¹¹C-methionine positron emission tomography-computed tomography (¹¹C-methionine PET-CT) co-registered with MRI (Met-PET/MRI^CR) in clinical decision making and surgical planning of patients with difficult to treat prolactinoma.

Methods

In eighteen patients with prolactinoma, referred to our tertiary referral centre because of intolerance or resistance for dopamine agonists (DA), Met-PET/MRI^CR was used to aid decision-making regarding therapy.

Results

Met-PET/MRI^CR was positive in 94% of the patients. MRI and Met-PET/MRI^CR findings were completely concordant in five patients, partially concordant in nine pat

SUBMITTER: Bakker LEH 

PROVIDER: S-EPMC9345807 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature