Coexistent cerebral small vessel disease and multiple infarctions predict recurrent stroke.

ABSTRACT:

Background and purpose

To investigate the association of different status of cerebral small vessel disease (CSVD) and infarction number with recurrence after acute minor stroke and transient ischaemic attack (TIA).

Methods

This study was a post hoc analysis of the Clopidogrel in High-risk Patients with Acute Nondisabling Cerebrovascular Events (CHANCE) trial, and includes 886 patients with acute minor stroke and TIA. The status of CSVD and infarction number was recorded for each individual. Infarction number were classified as multiple acute infarctions (MAIs≥2), single acute infarction (SAI =1), and non-acute infarction (NAI =0). The CSVD burden were grouped into non-CSVD (0 score) and CSVD (1-4 score). The primary outcome was a recurrent stroke at the 1-year follow-up. The

SUBMITTER: Tian Y 

PROVIDER: S-EPMC9349065 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature