COVID-19 infection and complications according to ABO blood group in the elderly: A population-based subcohort and meta-analysis.

ABSTRACT:

Background and objectives

It is reported that ABO antibodies have a role in COVID-19 infection and severity; however, ABO antibody titres vary with advanced age. The aim was to analyse the association between ABO blood group and risk of COVID-19 infection and complications in elderly patients, and to contrast this data with findings in the overall adult population.

Materials and methods

A prospective cohort study of the Navarre (Spain) population aged ≥60 years and a meta-analysis of published studies including participants of ≥60 years were carried out.

Results

In the Navarre elderly population, a higher risk of COVID-19 infection was identified in the A versus non-A and O group and lower risk in O versus non-O, with no significant association between hospitalization

SUBMITTER: Leache L 

PROVIDER: S-EPMC9349979 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature