Application of reverse vaccinology to design a multi-epitope subunit vaccine against a new strain of Aeromonas veronii.

ABSTRACT:

Background

Aeromonas veronii is one of the most common pathogens of freshwater fishes that cause sepsis and ulcers. There are increasing numbers of cases showing that it is a significant zoonotic and aquatic agent. Epidemiological studies have shown that A. veronii virulence and drug tolerance have both increased over the last few years as a result of epidemiological investigations. Cadaverine reverse transporter (CadB) and maltoporin (LamB protein) contribute to the virulence of A. veronii TH0426. TH0426 strain is currently showing severe cases on fish species, and its resistance against therapeutic has been increasing. Despite these devastating complications, there is still no effective cure or vaccine for this strain of A.veronii.

Results

In this regard, an immunoinformat

SUBMITTER: Islam SI 

PROVIDER: S-EPMC9358925 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature