Consensus on early detection of disease progression in patients with multiple sclerosis.

ABSTRACT:

Background

Early identification of the transition from relapsing-remitting multiple sclerosis (RRMS) to secondary progressive MS (SPMS) can be challenging for clinicians, as diagnostic criteria for SPMS are primarily based on physical disability and a holistic interpretation.

Objective

To establish a consensus on patient monitoring to identify promptly disease progression and the most useful clinical and paraclinical variables for early identification of disease progression in MS.

Methods

A RAND/UCLA Appropriateness Method was used to establish the level of agreement among a panel of 15 medical experts in MS. Eighty-three items were circulated to the experts for confidential rating of the grade of agreement and recommendation. Consensus was defined when ≥66% agreement

SUBMITTER: Meca-Lallana JE 

PROVIDER: S-EPMC9366521 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature