Hospital-Treated Infections and Increased Risk of Two EBV-Related Malignancies: A Nested Case-Control Study.

ABSTRACT:

Background

To assess the association of hospital-treated infections with the subsequent risk of two Epstein-Barr virus (EBV)-related malignancies, namely Hodgkin's lymphoma (HL) and nasopharyngeal carcinoma (NPC).

Methods

We performed a nested case-control study based on several national registers in Sweden. Cases were individuals newly diagnosed with HL or NPC during 1994-2016 in Sweden, according to the Swedish Cancer Register. For each case, we randomly selected five controls individually matched to the case on sex and year of birth from the general Swedish population. Hospital-treated infections (i.e., infections requiring either inpatient or outpatient hospital care) were identified from the Swedish Patient Register. Conditional logistic regression was used to estimate

SUBMITTER: Yang Y 

PROVIDER: S-EPMC9367337 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature