Vaccination counseling with and without excipient skin testing in patients with suspected allergic reactions to mRNA COVID-19 vaccines and patients with atopy.

ABSTRACT:

Background

Allergic reactions have been reported with mRNA vaccines for COVID-19 prevention. Patients perceived to be at higher risk for a reaction may be referred to an allergist, although evaluation strategies may differ between allergists.

Objective

Our aim was to determine outcomes of COVID-19 vaccinations in patients evaluated by an allergist using different approaches.

Methods

We conducted a retrospective case series evaluation of 98 patients seen at the University of Michigan Allergy Clinic for concerns regarding COVID-19 vaccination. Of these 98 patients, 34 underwent skin testing with polyethylene glycol (PEG) 2000 with or without PEG 3350/polysorbate 80 testing.

Results

Of the 34 patients on whom skin testing was performed, 16 underwent testing before

SUBMITTER: Khokhar D 

PROVIDER: S-EPMC9374488 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature